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The high-speed rail collision in southern Spain happened Sunday when the tail end of a train jumped the track, causing another train to derail. The official death toll rose to 41 by Tuesday morning.

Warming temperatures are forcing Antarctic penguins to breed earlier and that's a big problem for two of the cute tuxedoed species that face extinction by the end of the century, a study said.

It's unclear how many leaders have been asked to join the board, and the large number of invitations being sent out, including to countries that don't get along, has raised questions about the board's mandate and decision-making processes.

Indiana bullied its way into the history books Monday night, toppling Miami 27-21 to put the finishing touch on a rags-to-riches story, an undefeated season and the national title.

Trump to speak at the World Economic Forum amid rising international tension, Concerns about conditions at Texas detention center grow after 3 deaths, Indiana wins first national football title.

Samer Abouhamad set out from his parents' Massachusetts home — equipped with a bicycle, some supplies, and a dream.

NPR correspondents recap how funding cuts, layoffs and leadership and policy changes in the second Trump administration are affecting the Departments of Defense, State and Health and Human Services.

Medicaid is doing a novel payment system for the new, promising and expensive sickle cell treatment. It may become a model for all gene therapies being developed.

Hearings for President-elect Donald Trump's Cabinet nominees begin on Tuesday and ramp up on Wednesday. Here's what to look for.

Following the meeting between President Trump and his Chinese counterpart, NPR's Leila Fadel asks former U.S. Ambassador to China Nicholas Burns about Trump's relationship with Beijing.